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Although prior research has linked sleep and
2018-11-15
Although prior research has linked sleep and impulsivity in adolescence, little of this work has sought to explain adolescent behavior in terms of naturalistic differences in sleep quality. Instead, the bulk of prior sleep research focuses on experimental sleep restriction or sleep disorders (Beebe,
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AP1903 cost The present study is the first to
2018-11-15
The present study is the first to investigate whether increased cerebral blood flow (CBF) in the hippocampus is associated with aerobic fitness during childhood. This hypothesis cannot be directly tested with traditional BOLD techniques, given that BOLD can change depending on a number of factors re
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Unexpectedly the inhibition of EGFR
2018-11-15
Unexpectedly, the inhibition of EGFR induces expression of keratinocyte differentiation markers. Keratinocyte proliferation and differentiation are mutually incompatible: apparently, inhibiting cell proliferation diverts the cells into a differentiation pathway and consequently certain differentiati
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Nutlin3 There are a large number of reticulated pigmentation
2018-11-15
There are a large number of reticulated pigmentations that need to be distinguished, including dyskeratosis congenita (DKC), X-linked reticulate pigmentary disorder (XLRPD), Naegeli-Franceschetti-Jadassohn syndrome (NFJS), dermatopathia pigmentosa reticularis (DPR), DDD, reticulate acropigmentation
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Analysis of the calculated results shows that
2018-11-15
Analysis of the calculated results shows that the change of local elastic properties for the “pore-matrix” interface has the most impact on the effective elastic modulus. Fig. 18 shows the effective elastic modulus Eeff of the ceramics samples with modified elastic property of “pore-matrix” interfac
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br Introduction A balance sheet provides
2018-11-15
Introduction A balance sheet provides vital information regarding a bank’s financial position at any given point of time. The asset side includes loans forwarded to borrowers while the liabilities side, among other things, shows deposits made by customers (Diamond & Rajan, 1999). Banks not only s
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However the framework proposed by
2018-11-14
However, the framework proposed by Brunton et al. did not illustrate the sub-components and deliverables of AM; their work deliberately focused on only a single component of AM, which is Managing the Business. Based on Brunton et al., Emmitt (1999a, 2007) provided the first practical written guideli
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Because of its Gothic style architecture Myeong
2018-11-14
Because of its Gothic-style architecture, Myeong-dong Cathedral was selected to study its acoustical characteristics. The architectural acoustics and electro acoustics characteristics were compared and analyzed using acoustical measurements. This study was conducted as follows: investigation of cons
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The chemical abrasion mineral dissolution and
2018-11-14
The chemical abrasion, mineral-dissolution and isotope dilution technique, also termed “conventional”, which requires a high degree of control on many parameters to ensure highest data quality (Schaltegger et al., 2015). A multi-step procedure described as follows were performed at the State Key Lab
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br Clinical Importance and Key Message The Wong
2018-11-14
Clinical Importance and Key Message The Wong et al. study (Wong et al., 2016) is of epidemiological and clinical significance. The prevalence of VI as indexed in those with CKD is 36%, versus 13% among those without CKD. In the former, the odds ratio of VI among individuals without diabetes was 1
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Two other studies assessed the transcriptomic profile during
2018-11-14
Two other studies assessed the transcriptomic profile during the early hours of sepsis in whole blood (Lissauer et al., 2009; Johnson et al., 2007). Results of both studies revealed increased Aminoallyl-dCTP - Cy3 of TLR5 as well as mediators of apoptosis similar to the present study. Overall, the i
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Recently developed LEDGINs small molecule inhibitors of
2018-11-14
Recently developed LEDGINs, small molecule inhibitors of LEDGF/p75–IN interaction, allowed us to test this hypothesis. Indeed here we demonstrate: (i) a LEDGIN-mediated shift in lentiviral integration site distribution resembling LEDGF/p75 depletion (out of the body of actively transcribed genes, wi
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We also show that recruitment of MUS
2018-11-14
We also show that recruitment of MUS81-EME1 is required for SLX4com-mediated control of pro-inflammatory signaling. This suggests that, similar to what was previously reported for HIV biology (Laguette et al., 2014), the SLX4com likely represses LINE-1 retrotransposition through the endonucleolytic
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In order to test the
2018-11-14
In order to test the effect of anti-merozoite SCR7 in complement-mediated RBC invasion we used two types of antibodies, an anti-merozoite mouse monoclonal (mAb5.2) and polyclonal IgG from MSP142 vaccines (Otsyula et al., 2013). Use of mAb5.2 resulted in enhancement of RBC invasion above that of FS
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Autophagy also plays a role in response to treatment
2018-11-14
Autophagy also plays a role in response to treatment. An extensive literature suggests that autophagy can protect cancer cells against commonly used cancer therapies including a wide array of different drugs and radiation (Thorburn et al., 2014; Rebecca and Amaravadi, 2015). Such studies are the bas
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