• The following are the supplementary data

  2018-11-06

  

  The following are the supplementary data related to this article. Acknowledgments Introduction Inflammation, trauma and tumors may all lead to articular cartilage defects. However, the treatment of these defects remains a clinical challenge. Currently, clinical treatments for articular cartil

• Like pro NGF Fahnestock et al Peng et al pro

  2018-11-06

  

  Like pro-NGF (Fahnestock et al., 2001; Peng et al., 2004) pro-BNDF is the precursor protein of BDNF, which is abundant in the hippocampus (Barker, 2009; Bekinschtein et al., 2014; Lessmann and Brigadski, 2009; West et al., 2014). Pro-BDNF undergoes cleavage by a family of mammalian processing enzym

• Celecoxib We became interested in the potential role

  2018-11-06

  

  We became interested in the potential role of ADF genes and Celecoxib dynamics during osteoblast (OB) differentiation of hMSCs for several reasons. First, actin and microtubules are abundant in osteoblasts (Aubin et al., 1983; Arena et al., 1991). During OB differentiation, cell morphology is found

• The goal of this study was to

  2018-11-06

  

  The goal of this study was to identify an additional cell-surface marker that, when combined with CD133, could further distinguish and enrich PCFUs. Cell surface markers that were previously known to enrich non-pancreas progenitor cells, including CD71 (transferrin receptor), were screened. CD71 tra

• Interestingly in HCC cell lines

  2018-11-06

  

  Interestingly, in HCC cell lines the overexpression of SOX2 correlated with an increased cell invasion and sphere formation ability (Sun et al., 2013), suggesting a connection to an EMT and CSC phenotype. In HCC patients, SOX2 expression predicted poor overall survival and prognosis even after hepat

• br Results br Discussion We demonstrated a

  2018-11-05

  

  Results Discussion We demonstrated a significant positive correlation between the susceptibility of hiPSC-CMs to Mox-induced FPD prolongation and QT prolongation in healthy individuals within a certain concentration range. Thus, in vitro assays using hiPSCs derived from healthy individuals may

• Operationally CTS provides a marked improvement in the effic

  2018-11-05

  

  Operationally, CTS provides a marked improvement in the efficiency of isolating precision-modified iPSC lines compared with direct cloning-based methods, without extended hands-on time or a requirement for additional instrumentation. Following methodological refinements and legislating for effect ra

• In summary we show that calreticulin

  2018-11-05

  

  In summary, we show that calreticulin and TGF-β signaling intersect downstream of TGF-β receptors I and II. The presence of calreticulin permits TGF-β-mediated inactivation of GSK3β and thus promotes SNAIL2/SLUG-regulated repression of E-cadherin. This condition is sine qua non for the expression an

• Acceleration of neutrons in the uniform magnetic field by me

  2018-11-05

  

  Acceleration of neutrons in the uniform magnetic field by means of a radio-frequency flipper is well known and successfully used in physical experiments (see, e.g., Ref. [7]). The phenomenon of neutron acceleration in a strong alternating magnetic field (of amplitude ∼0.4T) was observed in Ref. [8].

• br Understanding patterns of informal care

  2018-11-05

  

  Understanding patterns of informal care provision between 2001 and 2011 In order to understand patterns of informal care provision between 2001 and 2011, a typology of caring transitions was used to capture change (or the lack of it) in the provision of informal care between 2001 and 2011 and the

• The results presented here are from a follow

  2018-11-05

  

  The results presented here are from a follow-up survey with attrition of the study cohort leading to modest responses in some communities that weakened the statistical power of our analysis. We have provided confidence intervals in all cases to enable consideration of whether statistically non-signi

• Despite intense scrutiny of the harms from

  2018-11-05

  

  Despite intense scrutiny of the harms from smoking, we are not aware of a prior study that has investigated, using data at the individual level, whether the risks of death from smoking differ across countries. We believe that such comparisons are best assessed on an additive or risk difference scale

• br Introduction Wet scrubbers are important air pollution

  2018-11-05

  

  Introduction Wet scrubbers are important air pollution control devices for cleaning large volumes of industrial effluent gas streams and they remove particulates and dangerous gases simultaneously by capturing into the droplets or pool of liquid and dissolving or absorbing into the liquid respect

• br Introduction Alternative methods of

  2018-11-05

  

  Introduction Alternative methods of fuel gas production and management of waste materials have been given due importance for many years (Liotta et al., 2014; Kovács et al., 2015) due to following facts: (i) With the ever-increasing per capita consumption of energy and exponentially rising populat

• br Introduction Core binding factor CBF is a heterodimeric

  2018-11-05

  

  Introduction Core binding factor (CBF) is a heterodimeric transcription factor composed of a DNA-binding RUNX subunit (encoded by one of three genes: RUNX1, RUNX2, or RUNX3) and a non-DNA-binding CBFβ subunit which increases the affinity of RUNX proteins for DNA. All three RUNX proteins as well a

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