Despite the dramatic changes in

2018-10-20

Despite the dramatic changes in bone morphology in OsxCre;iDTR mutants, bone marrow cellularity was unaffected compared with their control littermates (Figure 3A). Red blood cell and platelet numbers were unchanged in the blood of the OsxCre;iDTR mutant, but there was a 50% decrease in the white blo

Hippocalcin HPCA is a high affinity calcium

2018-10-20

Hippocalcin (HPCA) is a high-affinity calcium-binding protein restricted to the CNS and is most abundant in pyramidal cells of the hippocampus CA1 region (Kobayashi et al., 2012). During brain development HPCA expression increases sharply, concurrent with synapse formation (Saitoh et al., 1994). HPC

Dedifferentiation has been considered as one of the mechanis

2018-10-20

Dedifferentiation has been considered as one of the mechanisms rerouting cell fate by reverting differentiated cells to an earlier, more primitive phenotype. Interestingly, previous studies from both our group and others have demonstrated that dedifferentiation is a prerequisite for bone marrow stro

Hello world!

2018-07-29