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Operationally CTS provides a marked improvement in the effic
2018-11-05
Operationally, CTS provides a marked improvement in the efficiency of isolating precision-modified iPSC lines compared with direct cloning-based methods, without extended hands-on time or a requirement for additional instrumentation. Following methodological refinements and legislating for effect ra
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In summary we show that calreticulin
2018-11-05
In summary, we show that calreticulin and TGF-β signaling intersect downstream of TGF-β receptors I and II. The presence of calreticulin permits TGF-β-mediated inactivation of GSK3β and thus promotes SNAIL2/SLUG-regulated repression of E-cadherin. This condition is sine qua non for the expression an
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Acceleration of neutrons in the uniform magnetic field by me
2018-11-05
Acceleration of neutrons in the uniform magnetic field by means of a radio-frequency flipper is well known and successfully used in physical experiments (see, e.g., Ref. [7]). The phenomenon of neutron acceleration in a strong alternating magnetic field (of amplitude ∼0.4T) was observed in Ref. [8].
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br Understanding patterns of informal care
2018-11-05
Understanding patterns of informal care provision between 2001 and 2011 In order to understand patterns of informal care provision between 2001 and 2011, a typology of caring transitions was used to capture change (or the lack of it) in the provision of informal care between 2001 and 2011 and the
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The results presented here are from a follow
2018-11-05
The results presented here are from a follow-up survey with attrition of the study cohort leading to modest responses in some communities that weakened the statistical power of our analysis. We have provided confidence intervals in all cases to enable consideration of whether statistically non-signi
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Despite intense scrutiny of the harms from
2018-11-05
Despite intense scrutiny of the harms from smoking, we are not aware of a prior study that has investigated, using data at the individual level, whether the risks of death from smoking differ across countries. We believe that such comparisons are best assessed on an additive or risk difference scale
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br Introduction Wet scrubbers are important air pollution
2018-11-05
Introduction Wet scrubbers are important air pollution control devices for cleaning large volumes of industrial effluent gas streams and they remove particulates and dangerous gases simultaneously by capturing into the droplets or pool of liquid and dissolving or absorbing into the liquid respect
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br Introduction Alternative methods of
2018-11-05
Introduction Alternative methods of fuel gas production and management of waste materials have been given due importance for many years (Liotta et al., 2014; Kovács et al., 2015) due to following facts: (i) With the ever-increasing per capita consumption of energy and exponentially rising populat
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br Introduction Core binding factor CBF is a heterodimeric
2018-11-05
Introduction Core binding factor (CBF) is a heterodimeric transcription factor composed of a DNA-binding RUNX subunit (encoded by one of three genes: RUNX1, RUNX2, or RUNX3) and a non-DNA-binding CBFβ subunit which increases the affinity of RUNX proteins for DNA. All three RUNX proteins as well a
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br Grant Support This work was supported
2018-11-05
Grant Support This work was supported by a research grant from the National Science Council, Taiwan and the Institute of Biomedical Sciences, Academia Sinica (IBMS-CRC103-P02). Conflicts of Interest Author Contributions Introduction Because of late presentation and chemotherapy resistan
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br Detection of cancer by analysis of circulating cell
2018-11-05
Detection of cancer by analysis of circulating cell-free DNA (cfDNA) has received enormous attention over the past years (). cfDNA is released into the blood circulation by apoptotic and necrotic cells, and cancer patients have increased concentrations of cfDNA (). With the development of novel te
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miR a and miR b are two miRNAs of the
2018-11-05
miR-146a and miR-146b are two miRNAs of the same family that share the same seed sequence and only differ by two nucleotides at the 3′ end in their mature sequences. However, they are encoded by distinct genes located on separate chromosomes, which implies that they may fulfil distinct functions. In
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This study found that the
2018-11-05
This study found that the median CPT over time showed a greater decrease in the control group than the orexin agonist group. While both groups were given ranibizumab injections at baseline and week 4, the gene therapy group patients received a core vitrectomy, associated with subretinal gene therapy
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Cooney et al examined the permeation
2018-11-05
Cooney et al. (2014) examined the permeation stability of hydrogen through a Palladium Vanadium composite membrane at 500 °C for 120 h. The permeation stability of hydrogen was reported to have varied significantly. The membrane failed within the first 20 h due to poor mechanical integrity to a comb
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Introduction Th U dating of speleothems using
2018-11-05
Introduction 230Th/U dating of speleothems using highly precise and accurate state-of-the-art analytical methods, such as solution-based multi-collector inductively coupled calcitonin gene related peptide mass spectrometry (MC-ICPMS) has demonstrated the possibility of age inversions, i.e., the ag
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