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SB 203580 hydrochloride The elbow joint was immobilized
2018-11-06
The elbow joint was immobilized using a splint postoperatively. Intravenous prostaglandin E1 was administered for 3 days to prevent thrombosis recurrence. Moreover, ultrasonography conducted on Postoperative Day 5 showed a patent flow in the left brachial, proximal radial, and ulnar arteries, withou
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The molecular mechanisms that are involved
2018-11-06
The molecular mechanisms that are involved in inducing of alternative cell fates by increasing and reducing the amount of Sox2 during reprogramming remain unclear. An interesting finding was that Oct4 changes its partner and targets genes in a dose-dependent manner in human ESCs (Stefanovic et al.,
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Introduction Human embryonic stem cells
2018-11-06
Introduction Human embryonic stem syk inhibitor (hESC) were first derived in 1998 (Thomson et al., 1998) and in the short period since are beginning to realise their potential as a reproducible source of cells for clinical applications. In July this year, the United States Food and Drug Administrat
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Demonstrated here for the first time MKLP was observed in
2018-11-06
Demonstrated here for the first time, MKLP was observed in a hESC model system. Small MKLP particles are observed between mitotic spindles, large MKLP+ particles are observed aggregating in the lumen of neuroepithelial rosettes, and MKLP was not observed in the nucleus of hESC derived neural precurs
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Introduction The periosteum has recently been
2018-11-06
Introduction The periosteum has recently been recognized as a promising source of immature progenitor cells that are not yet committed to specific cell lineages and osteogenic progenitors. For osteogenic cell processing in tissue engineering, the periosteum has generally been utilized to prepare di
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br Experimental Procedures br Author Contributions br Acknow
2018-11-06
Experimental Procedures Author Contributions Acknowledgments The authors thank Drs. J. Toga and E. Yagi (Osaka University) for expression and purification of the recombinant LM511-E8 and Professor H. Ohmori (Kyoto University) for an electrophysiological study. We also thank Dr. E. Yamasaki,
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EZ Cap Reagent GG (3\' OMe) br Conclusions br Author con
2018-11-06
Conclusions Author contributions Conflicts of interest Acknowledgments Introduction Self-renewal is an integrated proliferation control that maintains undifferentiated states of stem cells. The integrated control is achieved by multilayered regulatory networks involving complex interp
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br Acknowledgments We thank Mrs
2018-11-06
Acknowledgments We thank Mrs Jessica Franzot for technical support with Western blotting. This work was supported by grants from the government of the Friuli Venezia Giulia Region (SPINAL project), the Fund for Transregional Cooperation (MINA project), and the IBRO Return Home Programme Grant (to
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br Materials and methods br Results br Discussion Microglia
2018-11-06
Materials and methods Results Discussion Microglia are resident immune ryanodine in the CNS that regulate innate immunity and participate in adaptive immune response (Hanisch and Kettenmann, 2007). However, the roles of microglia in AD pathology are still under debate. While there is signi
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The following are the supplementary data
2018-11-06
The following are the supplementary data related to this article. Acknowledgments Introduction Inflammation, trauma and tumors may all lead to articular cartilage defects. However, the treatment of these defects remains a clinical challenge. Currently, clinical treatments for articular cartil
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Like pro NGF Fahnestock et al Peng et al pro
2018-11-06
Like pro-NGF (Fahnestock et al., 2001; Peng et al., 2004) pro-BNDF is the precursor protein of BDNF, which is abundant in the hippocampus (Barker, 2009; Bekinschtein et al., 2014; Lessmann and Brigadski, 2009; West et al., 2014). Pro-BDNF undergoes cleavage by a family of mammalian processing enzym
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Celecoxib We became interested in the potential role
2018-11-06
We became interested in the potential role of ADF genes and Celecoxib dynamics during osteoblast (OB) differentiation of hMSCs for several reasons. First, actin and microtubules are abundant in osteoblasts (Aubin et al., 1983; Arena et al., 1991). During OB differentiation, cell morphology is found
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The goal of this study was to
2018-11-06
The goal of this study was to identify an additional cell-surface marker that, when combined with CD133, could further distinguish and enrich PCFUs. Cell surface markers that were previously known to enrich non-pancreas progenitor cells, including CD71 (transferrin receptor), were screened. CD71 tra
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Interestingly in HCC cell lines
2018-11-06
Interestingly, in HCC cell lines the overexpression of SOX2 correlated with an increased cell invasion and sphere formation ability (Sun et al., 2013), suggesting a connection to an EMT and CSC phenotype. In HCC patients, SOX2 expression predicted poor overall survival and prognosis even after hepat
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br Results br Discussion We demonstrated a
2018-11-05
Results Discussion We demonstrated a significant positive correlation between the susceptibility of hiPSC-CMs to Mox-induced FPD prolongation and QT prolongation in healthy individuals within a certain concentration range. Thus, in vitro assays using hiPSCs derived from healthy individuals may
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